Avogadro's number and the mass of an air molecule
Teaching Guidance
for 14-16

Theory, modelling, guessing and experimenting are all intertwined. Each step progressing from one idea to the next. However, this is a very cleaned up
view of the progress of science. Science is much messier than this and many ideas lead to dead ends and wrong predictions.
Knowing:
- The diameter of an air molecule, 4 x 10-10m,
- The space occupied by a molecule in liquid, (d3= {4 x 10-10}3= 64 x 10-30m3),
- The change of volume from a liquid to gas
You can calculate how many molecules there are in a room, (4m x 3m x 3m = 24 m3) giving about 5 x 1026 molecules.
This is in fact an estimate of the Avogadro number for a kilo-mole. A kilogram mole of any gas contains 6 x 1026molecules. It occupies 22.4 m3at 0 °C, or about 24 m3at room temperature, and atmospheric pressure.
Mass of an air molecule
Number of molecules in a room 24 m3, N = 5 x 1026
Mass of air molecules in a room 24 m3, M = Vp = 24 x 1.2 kg = 28.2 kg
Therefore, Mass of an air molecule = 28.2 / 5 x 10-26 = 5.6 x 10-26kg
When students know more about the structure of air (mainly nitrogen and oxygen) then the mass of their atoms can be estimated (they are fairly close in mass).
All this comes from imagining a theoretical picture, guided by the things we know about nature, such as Newton's Laws of Motion, and then making estimates and measurements.